Summary: Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein–protein and protein–nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations.
COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of biomolecular complexes
Shaikh, Abdul Rajjak;Oliva, Romina
2025-01-01
Abstract
Summary: Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein–protein and protein–nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations.File in questo prodotto:
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