Relaxation time estimation in MRI field could help clinical diagnosis. T1 and T2 changes can be related to tissues modification, being an effective tool for detecting the presence of several pathologies and measure their development, thus their estimation is a useful research field. Currently, most techniques work pixel-wise, and transfer the noise reduction task to post processing filters. A novel method for estimating spin-spin and spin-lattice relaxation times is proposed. The approach exploits Markov Random Field theory for modeling the unknown data and implements an a posteriori estimator in the Bayesian framework. The effect is the joint parameters estimation and noise reduction. Proposed methodology, with respect to already existing techniques is able to provide effective results while preserving details also in case of few acquisition or severe signal to noise ratio. The algorithm has been tested on both simulated and real datasets.

A Bayesian Approach for Relaxation Times Estimation in MRI

BASELICE, FABIO;FERRAIOLI, GIAMPAOLO;PASCAZIO, Vito
2016-01-01

Abstract

Relaxation time estimation in MRI field could help clinical diagnosis. T1 and T2 changes can be related to tissues modification, being an effective tool for detecting the presence of several pathologies and measure their development, thus their estimation is a useful research field. Currently, most techniques work pixel-wise, and transfer the noise reduction task to post processing filters. A novel method for estimating spin-spin and spin-lattice relaxation times is proposed. The approach exploits Markov Random Field theory for modeling the unknown data and implements an a posteriori estimator in the Bayesian framework. The effect is the joint parameters estimation and noise reduction. Proposed methodology, with respect to already existing techniques is able to provide effective results while preserving details also in case of few acquisition or severe signal to noise ratio. The algorithm has been tested on both simulated and real datasets.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11367/47623
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