Aims: Menopause is a period of significant physiological change that may be associated with increased body weight and obesity-related diseases. Many studies have been carried out to determine influences of estrogen depletion, resting energy expenditure (REE) decline and aging during menopause-related obesity. Methodology: In the present experiment, REE, body composition, activity of the autonomic nervous system, oxidative stress and food intake were measured in three groups of women: premenopause (n=40), post-menopause with hormone-replacement therapy (HRT) (n=40) and postmenopause without HRT (n=40). Results: In post-menopause women with HRT a significant increase was found in: 1) the sympathetic activity, measured by the power spectral analysis of the heart rate variability; 2) REE, measured by indirect calorimetry; 3) oxidative stress, measured by Free Radical Analytical System 4 (Fras-4) compared to the value of the other two, while fat mass, measured by Body Impedance Analysis (BIA), was reduced in favor of a recovery of free fat mass. Conclusion: The study emphasizes the important changes due to HRT on various components influencing body weight in menopause-women.

Activity of Autonomic Nervous System, Energy Expenditure and Assessment of Oxidative Stress in Menopause-women Using Hormone Replacement Therapy

TAFURI, Domenico;
2015

Abstract

Aims: Menopause is a period of significant physiological change that may be associated with increased body weight and obesity-related diseases. Many studies have been carried out to determine influences of estrogen depletion, resting energy expenditure (REE) decline and aging during menopause-related obesity. Methodology: In the present experiment, REE, body composition, activity of the autonomic nervous system, oxidative stress and food intake were measured in three groups of women: premenopause (n=40), post-menopause with hormone-replacement therapy (HRT) (n=40) and postmenopause without HRT (n=40). Results: In post-menopause women with HRT a significant increase was found in: 1) the sympathetic activity, measured by the power spectral analysis of the heart rate variability; 2) REE, measured by indirect calorimetry; 3) oxidative stress, measured by Free Radical Analytical System 4 (Fras-4) compared to the value of the other two, while fat mass, measured by Body Impedance Analysis (BIA), was reduced in favor of a recovery of free fat mass. Conclusion: The study emphasizes the important changes due to HRT on various components influencing body weight in menopause-women.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11367/39933
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact